Fexofenadine HCl, an active metabolite of terfenadine, has demonstrated to be a nonsedating Histamine H1 receptor antagonist. Mechanistic studies have reported that high concentrations of this compound can inhibit Cox-1 activity while low concentrations of Fexofenadine HCl inhibits Cox-2 activity.
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Structure
Product Description
| Details | |
|---|---|
| Chemical Name | FEXOFENADINE HCL |
| IUPAC Name | 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid hydrochloride |
| CAS Number | 138452-21-8 |
| Molecular Formula | C32H40CI NO4 |
| Synonyms | Fexofendine Hcl;FEXOFENADINE HCL;Fexofenadine Hydrochloride (200 mg);terfenidine carboxylate hydrochloride;CARBOXYTERFENADINE,TERFENADINECARBOXYLATE;Fexofenadine Hydrochloride (200 mg)F1E2890.996mg/mg(ai);2-[4-[1-hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]-butyl]phenyl]-2-methyl-propanoic acid hydrochloride;ALPHA,ALPHA-DIMETHYL-4-[1-HYDROXY-4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL]BUTYL]-BENZENEACETIC ACID HYDROCHLORIDE |
| Application | Anti-histamine |