Contact Information

9 Squares Building, Monalisha Township
Near Zanzarda Chowkdi, Junagadh 362001 (Gujrat, India)

(+ 91) 8866197888

(+ 91) 8866196888

health@worldprimeexport.com

Structure

CHLORPHENIRAMINE MALEATE

Product Description

Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
Details
Chemical Name CHLORPHENIRAMINE MALEATE
IUPAC Name (Z)-but-2-enedioic acid; 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
CAS Number 113-92-8
Molecular Formula C20H23ClN2O4
Synonyms alunex;piriex;Haynon;c-meton;ibioton;lorphen;piriton;teldrin;Puermin;allergin
Application An antagonist of the histamine H1-receptor.