Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist (IC50 > 32 μM).
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Structure
Product Description
| Details | |
|---|---|
| Chemical Name | Loratadine |
| IUPAC Name | Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate |
| CAS Number | 79794-75-5 |
| Molecular Formula | C22H23CIN2O2 |
| Synonyms | Lisino;Tadine;Civeran;Loranox;CLARITIN;Clarityn;CLARATYNE;SCH-29851;Claritine;LORATADINE |
| Application | Anti-histamine |